XIIth International Myeloma Workshop
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Educational Materials » PDF - 3.665 kBTable Of Contents (Spis treści)Myeloma Molecular Pathways/Cytogenics- Rafael Fonseca, MD
Mayo Clinic, Scottsdale, AZ - Role Of FISH In Myeloma Risk Stratification
- Hervé Avet-Loiseau, MD, PhD
Hematology Laboratory, University Hospital, and INSERM U892, Nantes, France - Genetic Changes In Myeloma: Prognostic Implications
- Johannes Drach - johannes.drach@meduniwien.ac.at
Medical University of Vienna, Department of Medicine I, Clinical Division of Oncology,Vienna, Austria - Redefining Risk Using Cytogenetic Changes
- Professor Gareth Morgan
The Institute of Cancer Research, London, United Kingdom - High-Throughput Molecular Profiling; Insights into Myeloma Pathogenesis And Clinical Outcome
- John D. Shaughnessy, Jr., Bart Barlogie
University of Arkansas for Medical Sciences, Little Rock, AR - New Insights into The Molecular Basis Of MM Pathogenesis And Prognosis
Myeloma - Signaling Pathways- Teru Hideshima, Hiroshi Ikeda, Constantine Mitsiades, Dharminder Chauhan, James E. Bradner, Nikhil C. Munshi, Paul G. Richardson, Kenneth C. Anderson
Jerome Lipper Myeloma Center, Dana-Farber Cancer Institute, Boston, MA, USA - Modulation Of Signaling Cascades By Inhibitors of Histone Deacetylase And Akt.
- Constantine S. Mitsiades - constantine_mitsiades@dfci.harvard.edu, Douglas W. McMillin, Jake Delmore, Joseph Negri, Steffen Klippel, Melissa Ooi, Nikhil C. Munshi, Paul G. Richardson, Kenneth C. Anderson
Department of Medical Oncology, Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston MA 02115, USA - Molecular Pathways Induced By Tumor – Microenvironment Interactions In Myeloma; Regulatory Role Of Heat Shock Proteins
- A. K. Stewart, R. E. Tiedemann, Y. Zhu
Mayo Clinic, Scottsdale, AZ - RNAi Vulnerability Map in Multiple Myeloma
- P. Leif Bergsagel, J. Jonathan Keats, Marta Chesi, W. Michael Kuehl
Mayo Clinic, Scottsdale, AZ - Targeting NFkß Signaling In Multiple Myeloma
- Anne Catherine Sprynski1, Dirk Hose2,3, Jérôme Moreaux1,4, Thierry Reme1,4, Michel Jourdan1, Philippe Bourin5,
Jil Corre5, Bart Barlogie6, John Shaughnessy6, Jean François Rossi1,4,7, Golsdchmidt Harmut2,3, Bernard Klein1,4,7
1. INSERM, U847, Montpellier, F34197 France
2. Medizinische Klinik V, Universitätsklinikum Heidelberg, INF410, Germany
3. Nationales Centrum für Tumorerkrankungen, INF350, D69115 Heidelberg, Germany
4. CHU Montpellier, Institute of Research in Biotherapy, F34285 France
5. EFS, Toulouse, France
6. Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, AR, USA
7. Université MONTPELLIER1, UFR Medecine, Montpellier, France - Cytokine Pathways In Myeloma Growth And Survival
Myeloma Immune and Antibody Targets- Qing Yi, MD, PhD
Department of Lymphoma and Myeloma, Division of Cancer Medicine, and the Center for Cancer Immunology Research, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA - Novel Antigenic Targets For Immunotherapy In Myeloma
- Diane F. Jelinek, Ph.D.
Mayo Clinic, Rochester, MN USA - Growth And Survival Signals In Myeloma: Roles For Baff and April
- Madhav V. Dhodapkar, MD
Yale University, New Haven, CT, USA - Immune Microenvironment In Myeloma Pathobiology
- Yu-Tzu Tai, Mariateresa Fulciniti, Pierfancesco Tassone, Paola Neri, Constantine Mitsiades, Teru Hideshima, Dharminder Chauhan, Paul Richardson, Kenneth C. Anderson, Nikhil C. Munshi
Dana-Farber Cancer Institute, Boston VA Healthcare System, Harvard Medical School, Boston, MA - Monoclonal Antibody - Based Therapies in Human Multiple Myeloma
- Surinder S. Sahota1, Niklas Zojer2, Gavin Babbage1, Debora Joseph-Pietras1, Nicola Weston-Bell1, Bernard Klein5, Karin Vanderkerken3, Pieter Sonneveld4, Karen Pulford6, Jason Rice1, Natalia Savelyeva1, Christian Ottensmeier1
1. Cancer Sciences Division, School of Medicine, University of Southampton, UK
2. Center for Oncology and Hematology, Wilhelminenspital, Vienna, Austria
3. Department Hematology and Immunology, Vrije Universiteit Brussel, Belgium
4. Department Hematology, Erasmus MC and Erasmus University, Rotterdam, The Netherlands
5. Institute of Research in Biotherapy, INSERM Unit 847, CHU Montpellier, Hopital Saint Eloi, Montpellier, France
6. Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, University of Oxford, UK - Defining Multiple Myeloma As A Target For DNA Fusion Gene Vaccines
Myeloma Microenvironment- G. David Roodman1,2, Yuko Hiruma1, Noriyoshi Kurihara1
1. University of Pittsburgh, Medicine/Hem-Onc, Pittsburgh, PA
2. VA Pittsburgh Healthcare System, Medicine/Hem-Onc, Pittsburgh, PA, USA - p62 – A Potential Target For Blocking Microenvironmental Support of Myeloma
- Irene M. Ghobrial MD, Aldo Roccaro MD PhD, Abdel Kareem Azab PhD, Judith Runnels PhD, Xavier Leleu MD PhD
Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA - Trafficking Of MM Cells: What Regulates Homing, Adhesion, And Mobilization Of Multiple Myeloma To And From The Bone Marrow Niches
- Angelo Vacca1 - a.vacca@dimo.uniba.it, Roberto Ria1, Domenico Ribatti2, Franco Dammacco1
1. Department of Internal Medicine and Clinical Oncology
2. Department of Human Anatomy, Histology and Embryology, University of Bari Medical School, I70124 Bari, Italy - Genes And Proteins Of Myeloma Endothelial Cells To Search Specific Targets Of The Tumor Vasculature
- Karin Vanderkerken, Elke De Bruyne, Sarah Deleu, Miguel Lemaire, Els Van Valckenborgh, Ivan Van Riet,
Eline Menu, Isabelle Vande Broek, Tomas Bos, Ben Van Camp
Part of this work was supported by a grant from the European Commission FP6 to MSCNET
Vrije Universiteit Brussel (VUB), Department Hematology and Immunology, Laarbeeklaan 103, B1090 Brussels, Belgium - Epigenetic Regulation Of Multiple Myeloma Within Its Bone Marrow Microenvironment
- Evangelos Terpos, Dimitrios Christoulas, Efstathios Kastritis, Magda Migkou, Maria Gavriatopoulou,
Meletios-Athanassios Dimopoulos
Department of Clinical Therapeutics, University of Athens School of Medicine, Athens, Greece - Novel Anti-Myeloma Agents And Bone Metabolism: Implications Into The Management Of Myeloma Bone Disease
Phase III Studies- Philippe Moreau
University Hospital, Nantes, France - Phase III Studies Published By the IFM (Intergroupe Francophone Du Myélome)
- S. Lonial, S. Giralt, B. Durie, B. Barlogie, E. Stadtmauer, K. Anderson, V. Rajkumar
- US Cooperative Group Trials
- Donna E. Reece, MD
Princess Margaret Hospital, University Health Network, Toronto, Canada - Canadian Collaborative Trials
- Boccadoro M, Palumbo A, Cavo M, Di Raimondo F, Bringhen S, Magarotto V, Larocca A, Mateos MV, Lahuerta JJ, Cibeira MT, Martínez J, Rosinol L, Bladé J, San Miguel J
GIMEMA (Italian Group for Adult Hematologic Diseases/Multiple Myeloma WorkingParty)
PETHEMA (Programa para el Estudio de la Terapéutica en Hemopatía Maligna) - The activity of Spanish and Italian Myeloma Groups
- P. Sonneveld
Erasmus MC, Rotterdam, The Netherlands - Phase III Studies by Northern European Groups in Multiple Myeloma
Phase II Studies- Paul Richardson MD1, Jacob Laubach MD1, Robert Schlossman MD1, Irene Ghobrial MD1, Teru Hideshima MD1, Constantine Mitsiades MD PhD1, Dharminder Chauhan PhD1, Noopur Raje MD1,2, Nikhil Munshi MD1,
Kenneth C. Anderson MD1
1. Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute
2. Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA - Novel Combination Therapies For The Treatment Of Relapsed/Refractory Multiple Myeloma:
Current Phase I/II Combinations - Palumbo Antonio1 - appalumbo@yahoo.com, Bringhen Sara1, Gay Francesca1, La Rocca Alessandra1,
Cavallo Federica1, Offidani Massimo2, Di Raimondo Francesco3, Boccadoro Mario1
1. Divisione di Ematologia Dell’Universita di Torino, Azienda Ospedaliera San Giovanni Battista, Torino, Italy
2. Clinica di Ematologia Azienda Ospedaliero-Universitaria, Ospedali Riuniti Ancona, Italy
3. Cattedra di Ematologia, Ospedale Ferrarotto, Catania, Italy - New Combination Approaches For Multiple Myeloma
- Robert Z. Orlowski, M.D., Ph.D.
The University of Texas M. D. Anderson Cancer Center Houston, Texas, USA - New Proteasome Inhibitors
- Shaji Kumar, M.D.
Mayo Clinic, Rochester, MN - Anti-Angiogenic Agents In Multiple Myeloma
- S. Vallet, N. Raje
Massachusetts General Hospital Cancer Center and DanaFarber Cancer Institute, Harvard Medical School, Boston, MA - Novel Bone Targeting Agents In Multiple Myeloma (MM)
- Martha Q. Lacy MD, Suzanne R. Hayman MD, Morie A. Gertz MD, Angela Dispenzieri MD, Philip R. Greipp MD, Stephen R. Zeldenrust MD PhD, Shaji Kumar MD, John A. Lust MD PhD, Joseph R. Mikhael MD, Vivek Roy MD, Stephen J. Russell MD PhD, Francis Buadi MD, Robert A. Kyle MD, Rafael Fonseca MD, S. Vincent Rajkumar MD, Keith Stewart MD, P. Leif Bergsagel MD, Sumithra J. Mandrekar Ph.D., Jacob B. Allred MS., Kristina Laumann, Melanie Thompson
Mayo Clinic, Rochester, MN, Mayo Clinic, Scottsdale, AZ, Mayo Clinic, Jacksonville, FL - Pomalidomide (CC4047) Plus Low-Dose Dexamethasone (Pom/Dex) As Therapy For Relapsed Multiple Myeloma
Transplant- Muzaffar H. Qazilbash MD - mqazilba@mdanderson.org, Sergio A. Giralt MD
Department of Stem Cell Transplantation and Cellular Therapy, University of Texas-MD, Anderson Cancer Center.
1515 Holcombe Boulevard 423, Houston, TX, 77030 - Current Status And Future Directions Of HCT In Myeloma: Moving Beyond High Dose Melphalan
- Donna M. Weber, MD
M.D. Anderson Cancer Center, Houston, TX USA - Timing Of Stem Cell Transplant In The Era Of Novel Agents
- Michele Cavo, Elena Zamagni, Paola Tacchetti, Michela Ceccolini, Nicoletta Testoni, Carolina Terragna, Annamaria Brioli, Caterina Pallotti, Lucia Pantani, Giulia Marzocchi, Sandra Durante, Alessandro Petrucci, Patrizia Tosi, Michele Baccarani
“Seragnoli” Institute of Hematology and Medical Oncology, Bologna University School of Medicine, Italy - Single Or Double Autologous Stem-Cell Transplantation Before And After The Era Of Novel Agents
- Bart Barlogie, Elias Anaissie, Frits van Rhee, John Crowley, John Shaughnessy Jr
Myeloma Institute for Research and Therapy, university of Arkansas for Medical Sciences, Little Rock, AR, USA;
Cancer Research and Biostatistics, Seattle, WA, USA - Curing Multiple Myeloma – Lessons From Total Therapy Protocols
- William Bensinger MD, Marcello Rotta, David Maloney
University of Washington, Fred Hutchinson Cancer Research Center, Seattle, WA - Allogeneic Stem Cell Transplantation For Multiple Myeloma: Maxi, Mini Or In Between
- Thierry Facon, M
Lille University Hospital, France - Post-Transplantation Maintenance In Patients With Multiple Myeloma
Consensus Panel- John Crowley
Cancer Research And Biostatistics - Statistical Issues In The Design And Analysis Of Clinical Studies In Myeloma
Novel combination therapies for the treatment of relapsed/refractory Multiple Myeloma: Current Phase I/II combinations » PDF - 1.570 kBPaul Richardson, Kenneth C. Anderson, Robert Schlossman, Irene Ghobrial, Constantine Mitsiades, Dharminder Chauhan, Teru Hideshima, Noopur Raje, Nikhil Munshi, Jacob Laubach
Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA